BioDIP Publications

Diabetologia 2012 Apr 18;55(4):1013-23

Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.

Knowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size.

Authors

Fava E, Dehghany J, Ouwendijk J, Müller A, Niederlein A, Verkade P, Meyer-Hermann M, Solimena M

Year

2012

PubMed ID

22252472

PubMed Link

PubMed

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