3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size.
Cell Rep 2014 Apr 24;7(2):398-411
LMF MPI-CBG
Neurobiology
Mutsenko VV, Bazhenov VV, Rogulska O, Tarusin DN, Schütz K, Brüggemeier S, Gossla E, Akkineni AR, Meißner H, Lode A, Meschke S, Ehrlich A, Petović S, Martinović R, Djurović M, Stelling AL, Nikulin S, Rodin S, Tonevitsky A, Gelinsky M, Petrenko AY, Glasmacher B, Ehrlich H
3D chitinous scaffolds derived from cultivated marine demosponge Aplysina aerophoba for tissue engineering approaches based on human mesenchymal stromal cells.
Int J Biol Macromol. 2017 Nov;104(Pt B):1966-1974
LMF & EMF CFCI
Biomaterials
Papadimitriou C, Celikkaya H, Cosacak MI, Mashkaryan V, Bray L, Bhattarai P, Brandt K, Hollak H, Chen X, He S, Antos CL, Lin W, Thomas AK, Dahl A, Kurth T, Friedrichs J, Zhang Y, Freudenberg U, Werner C, Kizil C
3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity.
Dev Cell. 2018 Jul 2;46(1):85-101
LMF CMCB, EMF & Histo CMCB
Neurobiology
Taubenberger AV, Bray LJ, Haller B, Shaposhnykov A, Binner M, Freudenberg U, Guck J, Werner C
3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments.
Acta Biomater. 2016 May;36:73-85
LMF CMCB, EMF & Histo CMCB
Cell Biology
Meinhardt A, Eberle D, Tazaki A, Ranga A, Niesche M, Wilsch-Bräuninger M, Stec A, Schackert G, Lutolf M, Tanaka EM
3D reconstitution of the patterned neural tube from embryonic stem cells.
Stem Cell Reports 2014 Dec 9;3(6):987-99
EMF MPI-CBG, LMF MPI-CBG
Cell Biology
Albert EA, Bökel C
A cell based, high throughput assay for quantitative analysis of Hedgehog pathway activation using a Smoothened activation sensor.
Sci Rep. 2017 Oct 30;7(1):14341
LMF CMCB
Cell Biology
Wagner N, Stephan M, Höglinger D, Nadler A
A Click Cage: Organelle-Specific Uncaging of Lipid Messengers.
Angew Chem Int Ed Engl. 2018 Oct 1;57(40):13339-13343
LMF MPI-CBG
Applied Chemistry
Ehret F, Vogler S, Kempermann G
A co-culture model of the hippocampal neurogenic niche reveals differential effects of astrocytes, endothelial cells and pericytes on proliferation and differentiation of adult murine precursor cells.
Stem Cell Res 2015 Nov 26;15(3):514-21
LMF DZNE
Neurobiology
McShane MP, Friedrichson T, Giner A, Meyenhofer F, Barsacchi R, Bickle M, Zerial M
A Combination of Screening and Computational Approaches for the Identification of Novel Compounds That Decrease Mast Cell Degranulation.
J Biomol Screen 2015 Jul 02;20(6):720-8
LMF MPI-CBG, Screening MPI-CBG
Medical Biology
Kumichel A, Kapp K, Knust E
A Conserved Di-Basic Motif of Drosophila Crumbs Contributes to Efficient ER Export.
