BioDIP Publications

Diabetologia 2013 Jul 27;56(7):1596-604

Effects of immunosuppression on alpha and beta cell renewal in transplanted mouse islets.

Immunosuppressive drugs used in human islet transplantation interfere with the balance between beta cell renewal and death, and thus may contribute to progressive graft dysfunction. We analysed the influence of immunosuppressants on the proliferation of transplanted alpha and beta cells after syngeneic islet transplantation in streptozotocin-induced diabetic mice.

Authors

Krautz C, Wolk S, Steffen A, Knoch KP, Ceglarek U, Thiery J, Bornstein S, Saeger HD, Solimena M, Kersting S

Year

2013

PubMed ID

23532258

PubMed Link

PubMed

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