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BioDIP Publications

Curr. Biol. 2013 Oct 7;23(19):1844-52

Fission yeast does not age under favorable conditions, but does so after stress.

Many unicellular organisms age: as time passes, they divide more slowly and ultimately die. In budding yeast, asymmetric segregation of cellular damage results in aging mother cells and rejuvenated daughters. We hypothesize that the organisms in which this asymmetry is lacking, or can be modulated, may not undergo aging.

Authors

Coelho M, Dereli A, Haese A, Kühn S, Malinovska L, DeSantis ME, Shorter J, Alberti S, Gross T, Tolić-Nørrelykke IM.

Year

2013

PubMed ID

24035542

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